N-Acetyl Cysteine

Increases glutathione to promote liver detoxification.
Enhances the elimination of heavy metals.
Antioxidant and mucolytic to help clear bronchial passages.
N-Acetyl cysteine promotes glutathione synthesis by donating sulfhydryl groups to support cysteine synthesis. Glutathione conjugation is a major phase II detoxification pathway responsible for making intermediate metabolites formed from phase I detoxification more water-soluble and therefore more easily excreted. N-Acetyl cysteine also enhances glutathione-S-transferase activity extracellularly to further support xenobiotic detoxification.
Heavy metal elimination is enhanced by N-Acetyl cysteine.This action is due to the thiol side chains of N-Acetyl cysteine binding metals to assist their removal from intracellular and extra cellular spaces. Studies have shown that N-Acetyl cysteine is capable of binding mercury, lead, and cadmium and copper.
N-Acetyl cysteine also has mucolytic properties, thereby assisting clearance of bronchial passages as shown in animal and human studies. N-Acetyl cysteine cleaves disulphide bonds that crosslink glycoproteins in mucous resulting in reduced mucous viscosity.

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